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Posted on 7/29/20 at 11:23 pm to Robot Santa
Santa, none of those 4 studies used the protocol I recommended which was the original recommendation when HCQ was being touted for COVID19. And it's interesting to note, that while all 4 studies judged the difference between the 2 groups to be clinically insignificant, in all 4 studies, even where the HCQ was being misdosed (IMHO), there were better outcomes.
I'm just telling you, dude, I've seen it work. And in a better ratio than these studies say. I don't understand the vitriol against this drug, other than it's old, it's off patent so it's generic and cheap, but it does something. The side effects have been known for years, that's nothing new. Patients must be monitored, especially at the higher doses used in COVID, but it's not particularly dangerous if used judiciously.
I'm just telling you, dude, I've seen it work. And in a better ratio than these studies say. I don't understand the vitriol against this drug, other than it's old, it's off patent so it's generic and cheap, but it does something. The side effects have been known for years, that's nothing new. Patients must be monitored, especially at the higher doses used in COVID, but it's not particularly dangerous if used judiciously.
Posted on 7/29/20 at 11:40 pm to phil4bama
Folks have been using it for years and years. The two drawbacks are that it’s cheap and Trump advocated for it. It’s sad that politics even get in the way of medical treatment. It’s fricking ridiculous
Posted on 7/30/20 at 12:31 am to Cobrasize
Can you imagine if all this happened 6 years ago and Obama peddled an unproven medication?
They'd have burned down the entire Penn. Avenue
They'd have burned down the entire Penn. Avenue
Posted on 7/30/20 at 12:36 am to stomp
Nah, the people that burn down shite are on Obama’s side
Posted on 7/30/20 at 5:53 am to Cobrasize
quote:Orange man bad, Cobra
Trump advocated for it. It’s sad that politics even get in the way of medical treatment. It’s fricking ridiculous
This post was edited on 7/30/20 at 5:56 am
Posted on 7/30/20 at 6:22 am to RollTide4Ever
Costa Rica has need for a standing army as the drug cartels oversee the protection of the people and their industry lol
This post was edited on 7/30/20 at 6:23 am
Posted on 7/30/20 at 6:39 am to stomp
quote:
Can you imagine if all this happened 6 years ago and Obama peddled an unproven medication?
They'd have burned down the entire Penn. Avenue
The people that held mass rallies to oppose things done by the Obama administration were part of the tea party movement.
I'll hang up and wait for the images of all the widespread violence at their rallies.
Posted on 7/30/20 at 7:19 am to JustGetItRight
Funny how the HCQ issue came up again. I just got an email about a study published in the prestigious NEJM using HCQ and azithromycin on COVID patients. The study concluded no benefits to the HCQ and zithromax group. Then I read the comments. Out of 148 comments, by doctors, physicians assistants and nurse practitioners, the large majority all said the same things: the study was poorly designed, the meds were given after the patients were already too sick, the regimen wasn’t correct, and an interesting one, you need to include zinc. This same majority also commented that HCQ works when done properly and early. There was also a vocal minority that tried to politicize the debate and some that believe the studies of HCQ’s failure to be real. And this is in one of our oldest and most prestigious medical journals, the New England Journal of Medicine.
Bottom line is the majority of practitioners (at least from what I see in the comments of this study) believe that HCQ along with azithromycin and zinc, given early and in the appropriate regimen, is an effective treatment against COVID19.
Bottom line is the majority of practitioners (at least from what I see in the comments of this study) believe that HCQ along with azithromycin and zinc, given early and in the appropriate regimen, is an effective treatment against COVID19.
Posted on 7/30/20 at 8:02 am to phil4bama
Well now you're moving the goalposts. First it was "they didn't administer it at the right time" and then when you're presented with ample evidence that they did, it's suddenly "well the dosage schedule was wrong". Come on man. Practically every study that has shown it to be effective has been highly flawed. The randomized, controlled studies have shown it to not be effective. There is no grand conspiracy among literally hundreds of thousands of medical professionals and scientists across the globe to deny this miracle treatment to millions. This isn't something being pushed by pharmaceutical companies who are trying to avoid a cheap drug beyond its patent life from solving the pandemic either. Studies have been done in countries where healthcare isn't a for-profit industry that show HCQ isn't a legitimate treatment option. The UK just did a large scale study that showed HCQ to be ineffective as a treatment for COVID, and there is one from Spain that is about to be published that -according to the doctor who led it-shows early intervention with HCQ to be ineffective.
This post was edited on 7/30/20 at 8:03 am
Posted on 7/30/20 at 8:02 am to phil4bama
quote:
Here’s a long, but very informative article on COVID19 and it’s effects and observations from the U of Cal-San Fransisco
This was as interesting and complete an article about the virus as I've read during the entire pandemic. Thanks phil.
Posted on 7/30/20 at 8:42 am to SummerOfGeorge
Best summation of where we are knowledge wise that I have seen.
Still more unknown than known which should not be surprising based on the short time we have been dealing with it.
This is not a tv show where everything can be solved in an hour. This is real life where knowledge takes real time.
For those that want to minimize this, let's wait and see what the long term consequences really are.
Still more unknown than known which should not be surprising based on the short time we have been dealing with it.
This is not a tv show where everything can be solved in an hour. This is real life where knowledge takes real time.
For those that want to minimize this, let's wait and see what the long term consequences really are.
Posted on 7/30/20 at 8:54 am to rcbama
Posted on 7/30/20 at 9:09 am to TideSaint
It seems like Alabama has ramped up testing incredibly even more over the last couple of weeks. We can't get enough drivers in here to cover all of the covid-related courier work we are getting right now.
Posted on 7/30/20 at 9:48 am to Funky Tide 8
Posted on 7/30/20 at 11:41 am to Funky Tide 8
It's the college kids going back to school. Every one of them must be tested. You've got a huge influx of tests in the next 2-3 weeks.
Posted on 7/30/20 at 11:50 am to phil4bama
Yea daughter just took hers a few minutes ago... said it was awful
Posted on 7/30/20 at 12:01 pm to Robot Santa
quote:
Well now you're moving the goalposts. First it was "they didn't administer it at the right time" and then when you're presented with ample evidence that they did, it's suddenly "well the dosage schedule was wrong". Come on man. Practically every study that has shown it to be effective has been highly flawed. The randomized, controlled studies have shown it to not be effective. There is no grand conspiracy among literally hundreds of thousands of medical professionals and scientists across the globe to deny this miracle treatment to millions. This isn't something being pushed by pharmaceutical companies who are trying to avoid a cheap drug beyond its patent life from solving the pandemic either. Studies have been done in countries where healthcare isn't a for-profit industry that show HCQ isn't a legitimate treatment option. The UK just did a large scale study that showed HCQ to be ineffective as a treatment for COVID, and there is one from Spain that is about to be published that -according to the doctor who led it-shows early intervention with HCQ to be ineffective.
I don't believe there's some huge conspiracy to discredit HCQ therapy. But I also don't believe it's ineffective. Having said that about the conspiracy, IF, and that's a big if, there were a conspiracy, you don't think Big Pharma has a vested interest in discrediting a possible treatment that costs pennies to produce while they sink billions of dollars worldwide on vaccines, treatments like Remdesivir, and other antivirals and established meds that are being touted as possible treatments? Hell, remdesivir is a failed treatment, first for Hepatitis C then when it failed for that, they tried Ebola and Marburg virus. It failed those too, so Gilead is sitting there with Remdesivir when COVID breaks out and they got lucky. But how lucky did they get? All it does is, according to all the data, is shorten your hospital stay by 4 days. The average stay is, I believe, 19 days. Remdesivir takes it to 15. If you're on a ventilator, recommended course is 2 vials on day 1 and 1 vial for 9 more days. Non-ventilated patients get 2 vials then 1 for 5 more days. If your response isn't sufficient, they extend it for the full 10 days. At a cost of $300 per vial. It's not a miracle drug. So don't be so naive as to think there's not an economic motive behind all this research. I hope it's not the only one, but it's definitely a factor. And if they have to fudge a little data to get approval, so be it. Guess who designs and pays for the trial studies to get approval? You think that might influence the results? You're damn right it does!
Posted on 7/30/20 at 12:02 pm to Bear88
quote:
Yea daughter just took hers a few minutes ago... said it was awful
So did mine. It was the deep nasal swab. I felt bad for her. It's horribly uncomfortable.
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