It's Game Day: No. 9 LSU At No. 4 Clemson In The Season Opener

No. 9 LSU opens the 2025 season Saturday night, on the road against No. 4 Clemson at Memorial Stadium.

Kickoff is set for 6:30 p.m. CT on ABC, and Chris Fowler and Kirk Herbstreit will call the game. Holly Rowe and Molly McGrath will report from the sidelines.

Clemson is currently a 4.5-point favorite, and the over/under is 57.5.

This will be just the fifth meeting between the two schools. LSU leads the overall series 3–1, including wins in both its 1958 and 2019 national championship seasons. Click HERE for the series history.

Preview, per LSU:

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LSU enters the season loaded with talent at the skill positions – some new additions and some familiar faces. It all starts with quarterback Garrett Nussmeier, who returns to Baton Rouge for his fifth and final year under center for the Tigers after throwing for 4,052 yards and 29 touchdowns in 2024. Nussmeier will have no shortage of weapons at his disposal in 2025, headlined by sophomore running back Caden Durham, receivers Chris Hilton, Barion Brown, Nic Anderson, and Aaron Anderson, alongside tight ends Trey’Dez Green and Bauer Sharp.

“This is about depth,” said head coach Brian Kelly on the 2025 roster. “We still have to go out and play and perform, but what’s different is it’s a mature group that has played a lot of football and we’re not going into a game where we can’t handle the moment.”

Defensively, the Tigers are in a great position with linebackers Harold Perkins and Whit Weeks back at full strength. In the secondary, LSU has playmakers all over the field, highlighted by transfer corner Mansoor Delane, safeties A.J. Haulcy and Tamarcus Cooley and corners Ashton Stamps and P.J. Woodland. In the trenches, the Tigers are anchored by fifth-year senior defensive lineman Jacobian Guillory and sophomore Dominick McKinley, alongside transfer Bernard Gooden, Gabe Reliford and edge rushers Jack Pyburn and Patrick Payton. It’s a group that, defensive coordinator Blake Baker says, has been a joy to coach.

“We haven’t played a game yet, but this is one of the most fun defenses I’ve ever coached,” Baker said. “It is a group of guys that are all pulling the rope in the same direction.”

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