re: Has anybody ever taken Lexapro and had a personality change?

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Here is another example where discoveries are coming so fast that it's difficult to keep up with developments, in this case medical technology.

I participated in a trial last year wherein my DNA was analyzed to determine which medicines would have the best effects, which dosages should be administered for optimum effects and which medicines should be avoided. The guesswork will mostly disappear when this procedure becomes common.

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That's awesome. A friend's wife is a physician working in the basement at MD Anderson cancer hospital in Houston. She works with rats and their DNA toward cancer cures. Tailoring cancer treatments based on a patient's DNA. (The chick is blonde, blue eyed, and about 20 pounds away from being verifiably H O T, btw. In addition to being so brilliant it's frickin scary).

I'm sure that a lot of one's neurotransmitter reuptake is defined by his DNA. I have to point out, however, that some people become chemically depressed because of environmental factors. Drug abuse comes to mind. But your point is very much appreciated and well taken.