re: Has anybody ever taken Lexapro and had a personality change?

First thing to accept re a drug like this is that NO physician on earth can throw you the right dosage the first time every time. And your doctor should have discussed this with you. There is no way to tell (no lab test, no imaging, etc.) how much serotonin and/or norepinephrine and/or other neurotransmitters are being bounced back and forth effectively within your brain cells. The dosage of an antidepressant is a shot in the dark. It's almost always going to be too high or too low to begin with. You are charged with sampling it for a month or more, returning to your physician, and giving him feedback. He/she will adjust the dose accordingly. And you may have to return to him/her several times before it's right.

Having said this I will postulate that either 1) you're finally who you're supposed to be. Congratulations! or 2) you're on too high a dose. The trick is to end the depression, not to become superman. Being superman for too long will inevitably end badly. And it won't take too long to get there. It won't last. There will be a crash.

I have tried 4 or 5 antidepressants, including Lexapro. They all gave me ADD out the whazoo. I finally had to accept that I don't have any neurotransmitter deficits. My brain chemistry is just fine. Increasing the seroronin makes me bounce around mentally like 3 hyperactive cheerleaders sharing one skull. My depression was self-imposed. I was allowing myself to go down dark paths of thought out of habit or something. Once I realized this I was able to treat my depression with counseling.