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Artificial intelligence yields new antibiotic
Posted on 2/28/20 at 7:25 am
Posted on 2/28/20 at 7:25 am
Using a machine-learning algorithm, MIT researchers have identified a powerful new antibiotic compound. In laboratory tests, the drug killed many of the world's most problematic disease-causing bacteria, including some strains that are resistant to all known antibiotics. It also cleared infections in two different mouse models.
The computer model, which can screen more than a hundred million chemical compounds in a matter of days, is designed to pick out potential antibiotics that kill bacteria using different mechanisms than those of existing drugs.
"We wanted to develop a platform that would allow us to harness the power of artificial intelligence to usher in a new age of antibiotic drug discovery," says James Collins, the Termeer Professor of Medical Engineering and Science in MIT's Institute for Medical Engineering and Science (IMES) and Department of Biological Engineering. "Our approach revealed this amazing molecule which is arguably one of the more powerful antibiotics that has been discovered."
In their new study, the researchers also identified several other promising antibiotic candidates, which they plan to test further. They believe the model could also be used to design new drugs, based on what it has learned about chemical structures that enable drugs to kill bacteria.
More here from MIT
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Posted on 2/28/20 at 8:57 am to Trumansfangs
We are locked in an arm's race with bacteria as odd as that sounds. They evolve, with help from poor health care practices, to become resistant. We come up with new drugs to kill them.
Folks tend to forget just how incredibly dangerous these things can be. We don't live in a time where half or more of your children don't survive to adulthood and where a scratch could conceivably kill you.
Folks tend to forget just how incredibly dangerous these things can be. We don't live in a time where half or more of your children don't survive to adulthood and where a scratch could conceivably kill you.
Posted on 2/28/20 at 10:56 am to Trumansfangs
A.I. will always provide help to the human population. It will never be a threat.
Posted on 2/28/20 at 2:42 pm to Kentucker
That gif is fantastic!!!!
Posted on 2/28/20 at 7:46 pm to Arksulli
quote:
Folks tend to forget just how incredibly dangerous these things can be. We don't live in a time where half or more of your children don't survive to adulthood and where a scratch could conceivably kill you.
Impeccably correct my friend !
Posted on 3/3/20 at 3:04 pm to Trumansfangs
quote:
the drug killed many of the world's most problematic disease-causing bacteria, including some strains that are resistant to all known antibiotics
Artificial intelligence just discovered chlorine bleach.
Posted on 3/3/20 at 3:22 pm to TheHarahanian
I know you're kidding, but some of this stuff is really fascinating.
"In laboratory tests against five species of bacteria, the researchers found that eight of the molecules showed antibacterial activity, and two were particularly powerful. The researchers now plan to test these molecules further, and also to screen more of the ZINC15 database.
The researchers also plan to use their model to design new antibiotics and to optimize existing molecules. For example, they could train the model to add features that would make a particular antibiotic target only certain bacteria, preventing it from killing beneficial bacteria in a patient's digestive tract."
"In laboratory tests against five species of bacteria, the researchers found that eight of the molecules showed antibacterial activity, and two were particularly powerful. The researchers now plan to test these molecules further, and also to screen more of the ZINC15 database.
The researchers also plan to use their model to design new antibiotics and to optimize existing molecules. For example, they could train the model to add features that would make a particular antibiotic target only certain bacteria, preventing it from killing beneficial bacteria in a patient's digestive tract."
Posted on 3/8/20 at 10:07 pm to Trumansfangs
Unfortunate side effect is that it makes your penis smaller. Looks like I'm gonna die from a bacteria infection guys.
Posted on 3/10/20 at 9:20 am to BFANLC
quote:
Looks like I'm gonna die from a bacteria infection guys.
Not me. I have a couple inches I could spare.
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