DavidTheGnome

This one seems extra trashy

It should be a crime to do what they did to the mom.

Absolutely ridiculous. Pay the debt down

Just got it on the OT

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He knows people want the Epstein Files released, and he’s working hard day and night to give us that.

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Bruh he was working hard day and night to prevent it. I can’t fathom being so indoctrinated to do a complete mental about face because you think it makes dear leader happy. This is some NK level sh!t

Insanity. Pay down the fvcking debt!

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What war has been started?


We are fighting organized crime.

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I can’t imagine going through life this naive and with my head so far buried up the admins arse

LINK

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Conclusions: The dopaminergic, stimulant-like, bupropion activities may be associated with its possible recreational value.

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Known as “welbys,” “wellies,” “dubs,” or “barnies,” its recreational use by oral or nasal routes was first described some 15 years ago (McCormick, 2002; Welsh and Doyon, 2002; GSK, 2016). More recently, reports of high-dose bupropion injecting have appeared as well (Baribeau and Araki, 2013), with people misusing the drug to get a “high” similar to the one obtained through other stimulants, such as cocaine.

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Bupropion is a cathinone derivative (Lewin et al., 2014); similar to remaining molecules of this class, one could argue that its diversion potential and reinforcement of misuse may be related to its dopaminergic and noradrenergic effects (Vento et al., 2013). Most bupropion abusers present with a history of drug addiction (Khurshid and Decker, 2004; Hill et al., 2007; Langguth et al., 2009; Kim and Steinhart, 2010; Reeves and Ladner, 2013; Yoon and Westermeyer, 2013); higher prevalence levels have been identified in inmates, and this has brought to bupropion removal of from some US prison formularies (Laird and Narayan, 2009; Phillips, 2012; Hilliard et al., 2013).

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Despite data collection limitations, and although further studies are clearly needed, both the literature and current EMA data may suggest that, in comparing these two molecules, bupropion appeared to be prone to misuse/abuse (Orsolini et al., 2015; Stassinos and Klein-Schwartz, 2016), whilst venlafaxine was more frequently reported as being associated with withdrawal. Present data may help the clinician in making a more informed decision about AD prescribing. One could argue, for example, that bupropion should be prescribed with caution in clients with a history of substance misuse,

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LINK

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The mechanism of reinforcement of misuse of bupropion is related to the effect on dopamine and norepinephrine neurotransmitter systems. When bupropion is crushed and ingested via nasal insufflation, a faster and higher affinity for neurotransmitters occurs, heightening the misuse potential. A literature search and illustrative case studies are presented demonstrating the misuse potential, along with a review of the clinical implications.

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It’s garbage but take your L on this. I understand you think you understand everything there is to know about this and I don’t doubt your credentials, but you’re being blinded by that as well. We as society have been told numerous times x, y, or z can’t be abused and yet we junkies will find ways to alter our minds.

I agree unless she’s ready rehab will do her no good. Does she actually need it though. A 19 year old drinking and snorting pills doesn’t mean she’s an addict

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Tough love will work if you will use it.

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lol no and I’m speaking from a wealth of experience.