re: Western Kentucky Parkway

Fair warning. I-65 around Louisville is an unmitigated clusterfrick right now (and likely for the next couple years) due to the Ohio River Bridges Project. Unless you want to stop in Louisville for whatever reason, I would avoid anything that brings you around here (and FWIW I live here in Louisville, it's a good city but traffic is awful right now).

ETA: Also the scenic drive through Kentucky on the Western Kentucky Parkway is nice. We really do have some pretty scenery here.