It starts by Jefferson going off his meds... right about now. By the time the evil poisons that keep his personality regulated have run their course and his body is "purified," (i.e. the start of the season), he'll conduct a pick 'em contest.
It's just like any other pick 'em you'll find anywhere else, so long as previous college football pools you've competed in have been grabbed by the ankles, shaken till they lose consciousness. When you win any other week, you wake up in a shallow grave, right?