re: Positive News: Another Dr. Touts Success of Hydroxychloroquine

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Concomitant bacterial pneumonia is incredibly rare in these patients. The potential benefit of azithromycin lies in its inherent anti inflammatory properties. I doubt changing to doxy would benefit patients.

These patients don’t die from their viral pneumonia, they die from the massive inflammatory response and acute respiratory distress syndrome when their lungs fill with fluid. Stopping the massive cytokine storm/inflammatory cascade that causes this is key I think, and I would guess trials looking at tocilizumab (IL-6 inhibitor) or anakinra (IL-1 inhibitor) will be more promising. Just my 2 cents as an ER doc who follows this stuff super closely, for obvious reasons.

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We do have another doc on here who said they prescribed Hydroxychloroquine only, and saw improvement only to see the patient go critical two days later due to a secondary bacterial pneumonia. It's one data point, but interesting nonetheless.